Case Reports
11 June 2025

Keratosis lichenoides chronica: a case report with dermatoscopic and ultrasonographic analysis

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We present the case of a 46-year-old woman with a long-standing history of linear erythematosquamous papules on the arms and thighs, which were unresponsive to treatment with topical corticosteroids. She also reported lesions typical of seborrheic dermatitis located on her face. After performing a clinical examination, dermatoscopy, high-frequency ultrasonography (HFUS), and a biopsy for histopathological examination, a diagnosis of keratosis lichenoides chronica (KLC) was obtained. Also known as Nekam disease, keratosis lichenoides chronica is a rare, chronic inflammatory skin disease characterized by diffuse, linearly arranged erythro- or erythematosquamous papules with a thin, keratotic plug.

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Citations

1. Aromolo IF, Giacalone S, Genovese G, et al. Keratosis lichenoides chronica: A case report and focused overview of the literature. Australas J Dermatol 2022;63. DOI: https://doi.org/10.1111/ajd.13713
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3. Böer A. Keratosis Lichenoides Chronica: Proposal of a Concept. Am J Dermatopathol 2006;28:260-7 DOI: https://doi.org/10.1097/00000372-200606000-00052
4. Menter MA, Morrison JGL. Lichen verrucosus et reticularis of Kaposi (porokeratosis striata of Nekam): a manifestation of acquired adult toxoplasmosis. Br J Dermatol 1976;94:645-54. DOI: https://doi.org/10.1111/j.1365-2133.1976.tb05164.x
5. Escanilla C, Truffello D, Cevallos C, et al. Keratosis lichenoides chronica: First case reported in Chile. Dermatol Online J 2019;25. DOI: https://doi.org/10.5070/D3255044073
6. Ozturk A, Acar A, Yaman B, Karaarslan I. Keratosis Lichenoides Chronica (Nekam Disease): Dermoscopic and in Vivo Reflectance Confocal Microscopy Findings. Dermatol Pract Concept 2023;e2023232. DOI: https://doi.org/10.5826/dpc.1304a232
7. Wang W-L, Lazar A: Lichenoid and interface dermatitis. In: McKee’s Pathology of the Skin. 4th ed. Edited by Calonje E, Brenn T, Lazar A, McKee P. Elsevier Saunders, 2012. DOI: https://doi.org/10.1016/B978-1-4160-5649-2.00007-X
8. Tang J, Liu F, Liao W, Zhu G. Treatment of Keratosis Lichenoides Chronica With Upadacitinib. JAMA Dermatol 2024;160:681-2. DOI: https://doi.org/10.1001/jamadermatol.2024.0755

How to Cite



Keratosis lichenoides chronica: a case report with dermatoscopic and ultrasonographic analysis. (2025). Dermatology Reports. https://doi.org/10.4081/dr.2025.10093