Case Reports
23 April 2025
Early Access
https://doi.org/10.4081/dr.2025.10220

Onset of vitiligo following contact dermatitis from eyeliner application in a 20-year-old female

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Vitiligo, eyelid depigmentation, contact dermatitis, Wood’s light examination, cosmetic-induced vitiligo
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Authors

Eugenia Veronica Di Brizzi
eugeniaveronica.dibrizzi@gmail.com
https://orcid.org/0000-0002-0278-2443
Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Gaetano Licata
https://orcid.org/0000-0002-0834-1331
Dermatology Unit, San Antonio Abate Hospital, Trapani, Italy.
Nicola Maria Giorgio
https://orcid.org/0009-0002-3103-5217
Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Giuseppe Argenziano
https://orcid.org/0000-0003-1413-8214
Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Caterina Mariarosaria Giorgio
https://orcid.org/0009-0003-2148-8914
Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.

Vitiligo is an autoimmune condition characterized by the destruction of melanocytes, leading to depigmented skin patches. Allergic contact dermatitis, triggered by allergens in cosmetics, can initiate localized immune responses that may progress to systemic immune dysregulation in genetically predisposed individuals. This case explores the potential role of allergic contact dermatitis in triggering vitiligo and proposes mechanisms underlying this association.

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Citations

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Schallreuter KU, Wood JM, Berger J. Low catalase levels in the epidermis of patients with vitiligo. J Invest Dermatol 1991;97:1081-5. DOI: https://doi.org/10.1111/1523-1747.ep12492612
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How to Cite



Onset of vitiligo following contact dermatitis from eyeliner application in a 20-year-old female. (2025). Dermatology Reports. https://doi.org/10.4081/dr.2025.10220
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