Case Reports
24 September 2025
Early Access
True leukonychia: case reports and review of the literature
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Leukonychia refers to the whitening of the nail plate. We identified 22 cases reported in the literature. This study presents two cases of idiopathic leukonychia from Saudi Arabia, which, to our knowledge, are the first reported cases in the region. The first case involves a 26-year-old male with a decade-long history of white discoloration affecting all fingernails. He exhibited low vitamin B12 and elevated thyroid-stimulating hormone (TSH) levels. The second case involves a 23-year-old female with asymptomatic white discoloration on five fingernails and a positive family history of leukonychia in her younger brother. This case series contributes to the limited knowledge of true leukonychia and emphasizes the importance of recognizing its benign nature and distinguishing it from other nail disorders.
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How to Cite
True leukonychia: case reports and review of the literature. (2025). Dermatology Reports. https://doi.org/10.4081/dr.2025.10405
Copyright (c) 2025 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
