Case Reports
12 July 2022
Vol. 14 No. 3 (2022)
https://doi.org/10.4081/dr.2022.9376

Skin reaction to COVID-19 vaccine: a report of 4 cases

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COVID-19, Vaccination, Skin reaction
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Authors

Mariabeatrice Bertolani
mariabeatrice.bertolani@gmail.com
Section of Dermatology, Department of Medicine and Surgery, University of Parma, Italy.
Maria Beatrice de Felici del Giudice
Section of Dermatology, Department of Medicine and Surgery, University of Parma, Italy.
Erminia Ridolo
Medicine and Surgery Department, Allergy and Clinical Immunology, University of Parma, Italy.
Francesco Pucciarini
Medicine and Surgery Department, Allergy and Clinical Immunology, University of Parma, Italy.
Claudio Feliciani
Section of Dermatology, Department of Medicine and Surgery, University of Parma, Italy.
Francesca Satolli
Section of Dermatology, Department of Medicine and Surgery, University of Parma, Italy.

Since the beginning of the covid-vaccine campaign, a lot of local and systemic dermatologic reactions happening after the administration of Coronavirus disease 2019 (COVID-19) vaccines have been described, even if their exact biological mechanism is still debated. In this paper, we report four cases of cutaneous manifestations that arose within ten days after the first dose of messenger RNA (mRNA)-based COVID-19 vaccination: one case of giant urticaria, one case of head and neck redness, and two cases of Erythema multiforme. In our experience, these reactions were mild and transient and all of them resolved, not recurring after the second dose, so these manifestations shouldn’t be considered as an absolute contraindication to the second dose of vaccine, that to date is fundamental.

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Skin reaction to COVID-19 vaccine: a report of 4 cases. (2022). Dermatology Reports, 14(3). https://doi.org/10.4081/dr.2022.9376
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