Case Reports
27 October 2022
Vol. 15 No. 2 (2023)
https://doi.org/10.4081/dr.2022.9571

Clinical, dermoscopic, and histopathologic findings of hidroacanthoma simplex: a case report and literature review

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Hidroacanthoma simplex, Borst-Jadassohn phenomenon, clonal seborrheic keratosis, Bowen's disease
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Authors

Maria Clara Almeida Issa
mariaclaraissa@gmail.com
https://orcid.org/0000-0003-3054-4714
Estácio de Sá University, Rio de Janeiro, Brazil.
Carolina Airão Destefani
https://orcid.org/0000-0002-2325-7808
Federal Fluminense University, Niteroi, Rio de Janeiro, Brazil.
Alice Guiotti de Alencar
Federal Fluminense University, Niteroi, Rio de Janeiro, Brazil.
Mayra Carrijo Rochael
Department of Pathology, Federal Fluminense University, Niteroi, Rio de Janeiro, Brazil.
Maria Claudia Almeida Issa
https://orcid.org/0000-0003-1031-7370
Department of Internal Medicine - Dermatology, Federal Fluminense University, Niteroi, Rio de Janeiro, Brazil.

Hidroacanthoma simplex (HS) is a rare benign intraepidermal tumor that originates in the acrosyringial portion of the eccrine duct. Clinically, they are well-defined lesions, flat or verrucous brownish plaque, and can be misdiagnosed with other types of benign or malignant tumors. Dermoscopy reveals small black globules and fine scales. The histopathology of HS is characterized by typical intraepidermal nests, well-circumscribed, composed of uniform basaloid and poroid cells within the acanthotic epidermis with cystic or ductal structures in the nests. We report a case of HS that changes its clinical appearance, dermoscopy, and histopathologic findings over time. Differential diagnoses included seborrheic keratosis, Bowen disease, melanoma, and malignant HS.

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as a potent differential diagnostic marker. Am J Dermatopathol 2014;36:655-60.
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How to Cite



Clinical, dermoscopic, and histopathologic findings of hidroacanthoma simplex: a case report and literature review. (2022). Dermatology Reports, 15(2). https://doi.org/10.4081/dr.2022.9571
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