Case Reports
21 April 2023
Vol. 15 No. 3 (2023)
https://doi.org/10.4081/dr.2023.9658

A case report of Hailey-Hailey disease treated with fractional carbon dioxide laser

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Hailey-Hailey disease, familial pemphigus, laser therapy, carbon dioxide laser
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Authors

Zivile Gabdrafike
zivile.aukstakojyte@gmail.com
Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, Medicine Academy, Kaunas; Department of Skin and Venereal Diseases, Hospital of the Lithuanian University of Health Sciences, Kauno Klinikos, Kaunas, Lithuania.
Monika Blazeviciute
Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, Medicine Academy, Kaunas; Department of Skin and Venereal Diseases, Hospital of the Lithuanian University of Health Sciences, Kauno Klinikos, Kaunas, Lithuania.
Ugne Janonyte
https://orcid.org/0000-0002-3924-5406
Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, Medicine Academy, Kaunas, Lithuania.
Jurgita Makstiene
Department of Pathology, Hospital of the Lithuanian University of Health Sciences, Kauno Klinikos, Kaunas, Lithuania.
Skaidra Valiukeviciene
Department of Skin and Venereal Diseases, Lithuanian University of Health Sciences, Medicine Academy, Kaunas; Department of Skin and Venereal Diseases, Hospital of the Lithuanian University of Health Sciences, Kauno Klinikos, Kaunas, Lithuania.

Hailey-Hailey disease (HHD), or familial benign pemphigus, is a rare genetic condition characterized by recurrent blisters and erosions with a predilection for intertriginous areas. There is no specific treatment for HHD. Topical and systemic treatments tend to provide temporary remission. Alternative treatment (surgical interventions such as dermabrasion, excision, and laser) has been shown to prolong remission. Considering the risk of complications associated with surgical modalities, laser is often preferred as an alternative for patients failing to respond to first-line therapies. We report a case of recalcitrant HHD successfully treated with a fractional ablative CO2 laser procedure (wavelength of 10600 nm, power of 7-10 W, 2-3 passes) on a 35-year-old female. The patient has a 7-year history of therapy-resistant HHD. A 2-month followup showed substantially resolved lesions, with mild erythema and post-inflammatory hyperpigmentation in treated areas.

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A case report of Hailey-Hailey disease treated with fractional carbon dioxide laser. (2023). Dermatology Reports, 15(3). https://doi.org/10.4081/dr.2023.9658
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