Case Reports
13 September 2023
Vol. 16 No. 1 (2024)
https://doi.org/10.4081/dr.2023.9731

A case of cutaneous variant of intravascular large B-cell lymphoma in which dermoscopy revealed telangiectasias associated with erythematous induration

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Cutaneous variant, dermoscopy, erythematous induration, intravascular large B-cell lymphoma, telangiectasia
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Authors

Shigeru Koizumi
https://orcid.org/0000-0002-7213-4708
Division of Dermatology, Asahi General Hospital, Asahi, Japan.
Yaei Togawa
togawa-yk@faculty.chiba-u.jp
Department of Dermatology, Chiba University Hospital, Chiba, Japan.
Yuka Saeki
Department of Dermatology, Chiba University Hospital, Chiba, Japan.
Ryo Shimizu
https://orcid.org/0009-0004-8104-639X
Division of Hematology, Asahi General Hospital, Asahi, Japan.
Michiyo Nakano
Division of Dermatology, Asahi General Hospital, Asahi, Japan.

Intravascular large B-cell lymphoma (IVLBCL) is a rare type of extranodal, diffuse, large B-cell lymphoma characterized by the selective growth of lymphoma cells within the lumen of small blood vessels, with no lymphadenopathy or masses. Herein, we report a cutaneous variant of IVLBCL that is rare in Asia. A healthy 73-year-old Japanese woman presented to our hospital with painful erythematous indurations and telangiectasia of the lower extremities, which was confirmed on dermoscopy. Physical examination revealed no systemic involvement, and laboratory parameters were within normal ranges. No abnormal fluorodeoxyglucose (FDG) uptake was detected on 18FDG positron emission tomography/computed tomography. Histopathological examination revealed proliferation and dilatation of blood vessels in the subcutis layer, occluded by CD20-positive atypical lymphoid cells. Thus, the patient was diagnosed with a cutaneous variant of IVLBCL without systemic symptoms. In conclusion, it is important to confirm telangiectasia using dermoscopy and perform skin biopsies in patients presenting with sudden-onset erythematous induration.

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A case of cutaneous variant of intravascular large B-cell lymphoma in which dermoscopy revealed telangiectasias associated with erythematous induration. (2023). Dermatology Reports, 16(1). https://doi.org/10.4081/dr.2023.9731
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