Case Reports
30 January 2024
Vol. 16 No. 4 (2024)
https://doi.org/10.4081/dr.2024.9853

Toxic epidermal necrolysis induced by COVID-19

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COVID-19, SARS-CoV-2, toxic epidermal necrolysis (TEN), Saudi Arabia
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Authors

Duaa Alahmadi
duaa.ahmady@gmail.com
Ministry of Health, Medinah, Saudi Arabia.
Azhar Ahmed
King Fahad General Hospital, Madinah, Saudi Arabia.
Esraa Shaheen
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Ahmed Ozbuck
Prince Mohammed Bin Abdulaziz Hospital of National Guard, Madinah, Saudi Arabia.
Walaa Borhan
https://orcid.org/0000-0003-2499-8189
Pathology Department, Taibah University, Saudi Arabia.

Toxic epidermal necrolysis (TEN) is a life-threatening acute mucocutaneous syndrome. It is characterized by keratinocyte necrosis and apoptosis, which affect more than 30% of the body’s surface. TEN is most commonly due to an altered immunological response to specific drugs, infections, and malignancies, or it can be idiopathic. The combination of TEN and COVID-19 can have a fatal outcome if not recognized and promptly treated. Therefore, fast reporting of such cases will draw doctors’ attention to quick and right intervention. In this article, we present a 66-year-old patient with a clinical presentation of toxic epidermal necrolysis along with a coexisting COVID-19 infection. To our knowledge, this is the first case of TEN in a patient diagnosed with SARS-CoV-2 infection in Saudi Arabia.

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Toxic epidermal necrolysis induced by COVID-19. (2024). Dermatology Reports, 16(4). https://doi.org/10.4081/dr.2024.9853
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