Articles
5 June 2009
Vol. 1 No. 10: Hemostasis and pregnancy, Milan, November 10, 2005
https://doi.org/10.4081/hmr.v1i10.340

Hemostatic changes in normal pregnancy

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Domenico Prisco
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Gabriele Ciuti
Michela Falciani
Normal pregnancy is accompanied by changes in the coagulation and fibrinolytic systems. These include a decrease in platelet count, increases in a number of clotting factors, a decrease in protein S levels, a significant fall in the activity of activated protein C and inhibition of fibrinolysis. These changes may be important for reducing intrapartum blood loss, but they determine an increased risk of thromboembolism during pregnancy and puerperium.

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Hemostatic changes in normal pregnancy. (2009). Hematology Meeting Reports (formerly Haematologica Reports), 1(10). https://doi.org/10.4081/hmr.v1i10.340