Towards therapeutic stimulations of gd T cells

M Malkovsky; M Wallace; DG McNeel; G Liu; G Mejia; M Kaikobad; P Waterman; E Samaniego; M Bonneville; JJ Fournie; H Sicard; F Poccia

doi:10.4081/hmr.v2i3.367

Abstracts

8 June 2009

Vol. 2 No. 3 (2006)

https://doi.org/10.4081/hmr.v2i3.367

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Towards therapeutic stimulations of gd T cells

Authors

M Malkovsky

support@pagepress.org

M Wallace

DG McNeel

G Liu

G Mejia

M Kaikobad

P Waterman

E Samaniego

M Bonneville

JJ Fournie

H Sicard

F Poccia

Most vaccine strategies are designed to elicit adaptive immune responses to a variety of microbial or tumor-associated antigens. These immune responses are predominantly mediated by αβ T cells, B cells and antibodies. Nevertheless, approximately 1-5% of human peripheral blood lymphocytes possess the surface gd T-cell receptor, predominantly expressing the Vγ9Vδ2 variable segments.