Articles
16 June 2009
Vol. 2 No. 15: Secondary Leukemias and leukemogenesis Rome, 3-4 November 2006

Defining The Translocation Mechanism In Therapy-Related Acute Promyelocytic Leukaemia

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Acute myeloid leukaemia (AML) occurring in children and younger adults is commonly associated with reciprocal balanced chromosomal translocations, which lead to the formation of chimaeric proteins that play a key role in mediating the leukaemic phenotype (reviewed 1).

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Defining The Translocation Mechanism In Therapy-Related Acute Promyelocytic Leukaemia. (2009). Hematology Meeting Reports (formerly Haematologica Reports), 2(15). https://doi.org/10.4081/hmr.v2i15.602