Original Article(s)
22 March 2023
Vol. 11 (2023)
Scanning Electron Microscopy coupled with Energy Dispersive Spectroscopy applied to the analysis of fibers and particles in tissues from colon adenocarcinomas
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Background: The mineral phases regulated as “asbestos” have a well-known role in disease development in the respiratory tract (e.g. mesothelioma, pulmonary carcinoma, asbestosis), but it is not clear their role in cancer development in other body sites, as in colon-rectum tract. Materials and Methods: In this work, seven colon tissues (healthy and neoplastic portions and an area “bridge” between them) from patients affected by colon adenocarcinoma – and living in a highly asbestos-polluted area - have been digested and the inorganic residual components collected on polycarbonate filters analyzed by means of Scanning Electron Microscopy (SEM) with annexed an Energy Dispersive Spectroscopy (EDS) for elemental chemical analysis. Results: The obtained results allow us to characterize serpentine phases in two of the seven analyzed patients. Moreover, calcium phosphate phases and other metal-rich particles have been observed inside the samples. Conclusions: SEM/EDS allowed us to morphologically observe and chemically analyze not only asbestos phases, but also other inorganic particles inside tissues deriving from colon adenocarcinomas.
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Scanning Electron Microscopy coupled with Energy Dispersive Spectroscopy applied to the analysis of fibers and particles in tissues from colon adenocarcinomas. (2023). Working Paper of Public Health, 11(1). https://doi.org/10.4081/wpph.2023.9586
Copyright (c) 2023 Alessandro Croce, Marinella Bertolotti, Stefania Crivellari, Marco Amisano, Elisabetta Nada, Federica Grosso, Laura Cagna, Caterina Rinaudo, Giorgio Gatti, Antonio Maconi
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
