Original Article(s)
26 January 2024
Vol. 11 (2023)
Radiological evaluation with Computed Tomography in the diagnosis of Medication-Related Osteonecrosis of the Jaw (MRONJ): RAD-ONJ observational study. A preliminary report of the study population
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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Background and Aims: Osteonecrosis of the Jaw (ONJ), recently renamed Medication-Related Osteonecrosis of the Jaw (MRONJ), is a recently recognized disease (2003), characterized by alterations including clinical signs and symptoms (not limited to bone exposure) together with jawbone radiological destruction, better assessed by Computed Tomography (CT) scan. We designed an observational (retrospective and prospective) study to systematically investigate the rate of occurrence of the various radiological signs of CT semeiotics, predefined in an appropriate table (i.e., focal and diffuse osteosclerosis, sequestrum, cortical disruption, periosteal reaction, osteolysis, etc.) in patients with MRONJ, diagnosed according to the criteria of the Italian SICMF-SIPMO recommendations (2020). Results: since March 2022, 120 patients with MRONJ were examined; 5 were considered not eligible due to lack of adequate CT images. Clinical data and radiological features of 115 patients were recorded and are under examination. Conclusions: the sample was higher than expected, and it appears sufficient to proceed to the evaluation of radiological features and draw conclusions about the investigated issue.
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How to Cite
Radiological evaluation with Computed Tomography in the diagnosis of Medication-Related Osteonecrosis of the Jaw (MRONJ): RAD-ONJ observational study. A preliminary report of the study population. (2024). Working Paper of Public Health, 11(1). https://doi.org/10.4081/wpph.2023.9786
Copyright (c) 2024 Antonella Fasciolo, Riccardo Campora, Vittorio Fusco, Costanza Massarino, Francesca Marengo, Giorgia Rossetti, Paola Brigo, Ivan Gallesio, Luca Benzi, Maura Rossi, Federico Monaco, Marco Ladetto, Antonio Maconi
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