Original Article(s)
Vol. 11 (2023)
Utility of clinical and laboratory data to estimate the probability of bacterial diarrhea diagnosed by stool multiplex Polymerase Chain Reaction assay in a pediatric population
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: 3 September 2023
Accepted: 6 October 2023
Accepted: 6 October 2023
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Aims: we estimated the probability of a positive result for the most common bacterial causal agents of diarrhea, such as Campylobacter spp., Salmonella spp., Shigella/Enteroinvasive Escherichia coli, Yersinia enterocolitica or Shiga toxin-producing Escherichia coli by a stool multiplex Polymerase Chain Reaction (PCR) assay in a pediatric population evaluated at the Pediatric and Pediatric Emergency Unit, Children Hospital of the Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy, during the period April 2022 - July 2023. Methods: we analyzed the clinical data collected by the Pediatrician on the stool sample request form along with complete blood count and C-Reactive Protein (CRP). Results: in our case series, the presence of blood/mucus in stool along with an increased value of CRP are independently associated with a positive result diagnosed by molecular method for bacterial diarrhea caused by the aforementioned pathogens. Conclusions: the results proposed in this paper can be of help in hospital settings without the availability of a stool multiplex PCR assay to estimate the probability of bacterial diarrhea in a pediatric patient.
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Citations
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How to Cite
Utility of clinical and laboratory data to estimate the probability of bacterial diarrhea diagnosed by stool multiplex Polymerase Chain Reaction assay in a pediatric population. (2024). Working Paper of Public Health, 11(1). https://doi.org/10.4081/wpph.2023.9842
Copyright (c) 2024 Christian Leli, Valentina Pizzo, Marcella Cerrato, Salvatore Castaldo, Annalisa Roveta, Maria Matilde Ciriello, Enrico Felici, Antonio Maconi, Andrea Rocchetti
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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