Review Article(s)
7 November 2024
Vol. 12 (2024)
https://doi.org/10.4081/wpph.2024.9897

PANDAS syndrome: diagnosis, physiopathology, etiology and treatments

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PANDAS, obsessive-compulsive disorder, cognitive-behavioral treatments
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Chiara Volpini
https://orcid.org/0009-0004-1593-986X
SSA Psicologia, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Rossella Sterpone
SSA Psicologia, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Monica Franscini
SSA Psicologia, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Valentina Manfredi
valentina.manfredi@ospedale.al.it
https://orcid.org/0000-0001-8705-7381
SSA Psicologia, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.

The aim of this paper is to carry out a narrative review of the main contributions in the literature relating to PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) syndrome. The literature search was carried out using Pubmed, Psycinfo, and PsycArticles databases.

The diagnostic criteria and etiology are still debated and objects of research. Several studies suggest that streptococcal infections induce an immunological response that causes basal ganglia modifications. Currently, treatments in practice are pharmacological, immunological, surgical, and psychological, used in combination for greater efficacy. Given the complexity of the syndrome, further studies are needed to better define the syndrome and lead towards targeted treatments.

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PANDAS syndrome: diagnosis, physiopathology, etiology and treatments. (2024). Working Paper of Public Health, 12(1). https://doi.org/10.4081/wpph.2024.9897
Copyright (c) 2024 Chiara Volpini, Rossella Sterpone, Monica Franscini, Valentina Manfredi Creative Commons License

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